PMDD Comprehensive Glossary
CLICK ON THE TERM TO SEE DEFINITIONPMDD (Premenstrual Dysphoric Disorder)
A severe hormone sensitivity disorder where emotional, physical, and cognitive symptoms occur in the luteal phase and resolve after menstruation begins.
PMS (Premenstrual Syndrome)
Milder premenstrual symptoms that do not cause the functional impairment seen in PMDD.
PME (Premenstrual Exacerbation)
When an existing condition worsens significantly before your period.
Luteal Phase
The 10–14 days before your period when PMDD symptoms appear.
Follicular Phase
The phase after menstruation ends and before ovulation. Most people with PMDD feel stable here.
Ovulation
The midpoint of the cycle; PMDD symptoms often begin shortly after ovulation.
Hormonal Sensitivity
The brain’s intense reaction to normal hormonal fluctuations — the root cause of PMDD.
Estrogen Sensitivity
Emotional or physical reactions triggered by estrogen changes.
Progesterone Sensitivity
A strong reaction to rising progesterone levels after ovulation.
Serotonin Dip
A drop in serotonin during the luteal phase that worsens mood, anxiety, and sleep.
Dopamine Dysregulation
Fluctuations that impact motivation, focus, and emotional reward.
Emotional Dysregulation
Difficulty managing emotions, leading to exaggerated emotional responses.
Luteal Rage
Sudden, intense irritability or anger during PMDD.
Rejection Sensitivity
Feeling deeply hurt by perceived rejection or criticism during PMDD.
Intrusive Thoughts
Unwanted, distressing thoughts that disappear once menstruation begins.
Derealization
Feeling disconnected from your surroundings.
Depersonalization
A sense of detachment from oneself during PMDD episodes.
Brain Fog
Difficulty thinking clearly, remembering, or focusing during the luteal phase.
Executive Dysfunction
Difficulty starting tasks, organizing, planning, or making decisions.
Overstimulation
Sensitivity to noise, lights, movement, or social interaction.
Attachment Sensitivity
Feeling unsure about relationships due to hormonal emotional changes.
Social Withdrawal
The instinct to isolate due to overwhelm or emotional fatigue.








